Preconditioning and postconditioning: from bench to bedside
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چکیده
منابع مشابه
Ischaemic postconditioning: from bench to bedside ..
The increase in the incidence of ischaemic heart disease and acute myocardial infarction (AMI) in both highand lowincome countries necessitates the development of myocardial salvaging/protection interventions, to be applied alongside standard reperfusion therapies. Although the phenomenon of ischaemic preconditioning (IPC) is associated with the desired protective capacity, the necessity of its...
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schemic preconditioning is the one maneuver that has onsistently been shown to reduce myocardial necrosis due o ischemia/reperfusion injury in experimental models (1). rief coronary occlusions of a few minutes to 10 min ollowed by brief reperfusion periods markedly reduce the ize of a subsequent myocardial infarction (MI) induced by longer coronary artery occlusion followed by reperfusion. he a...
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A steadily increasing number of investigations demonstrate that preconditioning with volatile anesthetics attenuates the deleterious effects of myocardial ischemia and reperfusion injury by an ischemic preconditioning-like mechanism. Thus volatile anesthetics may represent the best choice for anesthesia of patients at risk for myocardial ischemia. However, factors such as old age, coexisting co...
متن کاملFrom bench to bedside
Because the microcirculation has emerged as an important reanimation target, appropriate methods to monitor the microcirculatory function are crucial. Several teams have now succeeded in crossing this bridge from bench to bedside, but the choice of the tissues of interest remains a debate. The potential accessible vascular beds that doctors could use in reanimation strategies and the relationsh...
متن کاملFrom Bench to Bedside
Since the initial experiments nearly a decade ago, remarkable progress has been made in the field of vascular gene transfer, and trials with human subjects already are under way. The potential of vascular wall gene transfer as therapy for various vascular diseases is considerable.1,2 The purpose of this review is 2-fold: (1) to delineate the methods and principles underlying vascular gene trans...
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ژورنال
عنوان ژورنال: SA Heart
سال: 2017
ISSN: 2071-4602
DOI: 10.24170/6-1-2008